Abnormal Nerve Conduction Parameters in Young Diabetic Patients at Diagnosis
Autor: | Rashedul Islam, Rumana Habib, Aminur Rahman, Nirmalendu Bikash Bhowmik, Zahid Hassan, Amirul Haque |
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Rok vydání: | 2016 |
Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Snap Motor nerve medicine.disease Nerve conduction velocity chemistry.chemical_compound medicine.anatomical_structure Fructosamine Endocrinology chemistry Internal medicine Diabetes mellitus Materials Chemistry medicine Nerve conduction study Cardiology Ulnar nerve business Sensory nerve |
Zdroj: | BIRDEM Medical Journal. 5:14-19 |
ISSN: | 2305-3720 2305-3712 |
DOI: | 10.3329/birdem.v5i1.28368 |
Popis: | Background and Objectives: Diabetes in the young patients, less than 30 years of age, usually has sudden onset and severe hyperglycemia who are resistant to ketosis. Taking the advantage of this uniqueness of this group of patients the present study was aimed to evaluate their peripheral nerve functional status, explore its relationship with glycemic status and find out utility of nerve conduction study for detection of neuropathy at diagnosis to introduce timely intervention in the necessary cases.Materials and Methods: A total number of 32 newly diagnosed untreated diabetic patients, age 30 years or less, consecutively attending the BIRDEM Out-patient department were recruited. Age-matched healthy subjects (n=30) with no family history of diabetes served as controls. Motor and sensory conduction velocities (NCV), distal latencies (DL), compound muscle and sensory nerve action potentials (CAMP, SNAP) of ulnar, peroneal and sural nerves were studied following standard protocol. Glucose was determined by glucose-oxidase, Fructosamine by enzymatic colorimetric method.Results: Ulnar motor NCV (m/sec, mean±SD) was significantly slower in diabetic group compared to the controls [58.29±6.88 vs 66.56±6.13; p |
Databáze: | OpenAIRE |
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