PHYTOESTROGENS EFFECT ON SEXUAL HORMONES LEVEL AND FERTILITY OF RATS

Autor:	E. V. Somova, A. I. Gladkova, N. A. Karpenko, Yevheniia Koreneva, Elina Chistyakova, Nataliia Selyukova
Rok vydání:	2010
Předmět:	Endocrinology Endocrinology Diabetes and Metabolism Pathology and Forensic Medicine
Zdroj:	Problems of Endocrine Pathology. 31:86-93
ISSN:	2518-1432 2227-4782
Popis:	The influence of 30-day application of phytoestrogens compound to postpubertal male and female rats on the level of sexual hormones, gametes maturation and fertilization capacity was experimentally studied. Long-term phytoestrogenes supplies into animal’s organism bring out substantial changes in the level of sexual hormones. In females different estradiol contents are levelled at the estrus-diestrus stages that is typical for intact females. In males there was a considerable increase of estradiol, in a lesser degree — testosterone. Hence, the testosterone-esrtadiol ratio is altered. Morphological structural changes in male and female gametes, decreased spermatozoa motility, impaired embryonic implantation, a high rate of embryonic mortality are observed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5258004f4e5bcfd01095bd9a7d18aab5 https://doi.org/10.21856/j-pep.2010.1.13 Zobrazit plný text záznamu