PHYTOESTROGENS EFFECT ON SEXUAL HORMONES LEVEL AND FERTILITY OF RATS
Autor: | E. V. Somova, A. I. Gladkova, N. A. Karpenko, Yevheniia Koreneva, Elina Chistyakova, Nataliia Selyukova |
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Rok vydání: | 2010 |
Předmět: | |
Zdroj: | Problems of Endocrine Pathology. 31:86-93 |
ISSN: | 2518-1432 2227-4782 |
Popis: | The influence of 30-day application of phytoestrogens compound to postpubertal male and female rats on the level of sexual hormones, gametes maturation and fertilization capacity was experimentally studied. Long-term phytoestrogenes supplies into animal’s organism bring out substantial changes in the level of sexual hormones. In females different estradiol contents are levelled at the estrus-diestrus stages that is typical for intact females. In males there was a considerable increase of estradiol, in a lesser degree — testosterone. Hence, the testosterone-esrtadiol ratio is altered. Morphological structural changes in male and female gametes, decreased spermatozoa motility, impaired embryonic implantation, a high rate of embryonic mortality are observed. |
Databáze: | OpenAIRE |
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