Popis: |
As a clinical entity, growth hormone (GH) deficiency in adulthood has previously received little attention. This has been due in part to a traditional view that GH is only of physiological importance during childhood and adolescence, when its effects are most visible and dramatic, despite the fact that GH secretion normally continues throughout adult life. More importantly, the limited availability of pituitary-derived human GH in the past meant there was no possibility of exploring its effects in GH-deficient adults. This problem has been overcome with the introduction of recombinant human GH, in potentially unlimited quantities. |