Clinical Blood Cholinesterase Measurements for Monitoring Pesticide Exposures

Autor: J. D. Henderson, Stephanie Padilla, J. R. Sanborn, J. E. Billitti, B. W. Wilson
Rok vydání: 1995
Předmět:
Zdroj: Enzymes of the Cholinesterase Family ISBN: 9781489910530
DOI: 10.1007/978-1-4899-1051-6_66
Popis: Measurement of blood cholinesterase (ChE) activity, especially acetylcholinesterases (AChE, EC 3.1.1.7) and butyrylcholinesterases (BChE, EC 3.1.1.8), is of worldwide interest and importance. They are one of the few biomarkers that function both as an indicator of exposure and also as evidence of an adverse effect. Determining blood ChEs is required for monitoring farmworkers in the state of California in the United States. In addition, ChE determinations are used in emergency wards to diagnose exposure to anti-ChEs, as part of the submissions to regulatory agencies to set safe levels of pesticides, to monitor wildlife and their exposure to dangerous anti-ChE chemicals, and to provide evidence of the use or escape of nerve gases.
Databáze: OpenAIRE