Helicobacter pylori as a Possible Bacterial Focus of Chronic Urticaria

Autor: W. Domschke, E.-C. Foerster, R. Brehler, S. Wustlich, T. Pohle, Thomas A. Luger
Rok vydání: 1999
Předmět:
Zdroj: Dermatology. 198:130-132
ISSN: 1421-9832
1018-8665
Popis: Background: Chronic urticaria is one of the most frequent skin diseases. Its cause, however, remains unsolved in a large number of cases. Recent investigations pointed to a potential role of Helicobacter pylori infection of the upper gastrointestinal tract as a possible causative agent in chronic urticaria. Objective: The aim of this study was to examine the effect of a 14-day eradication therapy on chronic urticaria. Methods: Thirty patients with chronic urticaria and confirmed H. pylori infection were treated with amoxicillin and omeprazole. Follow-up was conducted over a period of 6 months concerning eradication of H. pylori and remission of urticaria. Results: Only 8 out of 30 patients (26.7%) showed clinical improvement or disappearance of their urticarial symptoms. Conclusion: Though our results do not support the preliminary data of previous studies, the role of H. pylori as a possible bacterial focus of chronic urticaria has to be further investigated.
Databáze: OpenAIRE