LesionAir: An Automated, Low-Cost Vision-Based Skin Cancer Diagnostic Tool

Autor: Edward Perez, Jay D. Carlson, Tyler D. Wortman, Alexander H. Slocum
Rok vydání: 2018
Předmět:
Zdroj: Journal of Medical Devices. 12
ISSN: 1932-619X
1932-6181
DOI: 10.1115/1.4039209
Popis: Current techniques for diagnosing skin cancer lack specificity and sensitivity, resulting in unnecessary biopsies and missed diagnoses. Automating tissue palpation and morphology quantification will result in a repeatable, objective process. LesionAir is a low-cost skin cancer diagnostic tool that measures the full-field compliance of tissue by applying a vacuum force and measuring the precise deflection using structured light three-dimensional (3D) reconstruction. The technology was tested in a benchtop setting on phantom skin and in a small clinical study. LesionAir has been shown to measure deflection with a 0.085 mm root-mean-square (RMS) error and measured the stiffness of phantom tissue to within 20% of finite element analysis (FEA) predictions. After biopsy and analysis, a dermatopathologist confirmed the diagnosis of skin cancer in tissue that LesionAir identified as noticeably stiffer and the regions of this stiffer tissue aligned with the bounds of the lesion. A longitudinal, full-scale study is required to determine the clinical efficacy of the device. This technology shows initial promise as a low-cost tool that could rapidly identify and diagnose skin cancer.
Databáze: OpenAIRE