Design and Scale-up of a Co-processing Technology to Improve Powder Properties of Drug Substances

Autor:	Mark Lindrud, Nathaniel Kopp, David Buckley, Gregory Lane, Deniz Erdemir, Daniel S. Hsieh, Whitney Nikitczuk, Jing Tao, Adriene Malsbury, Vivek Daftary, Joshua Engstrom
Rok vydání:	2019
Předmět:	Active ingredient Materials science 010405 organic chemistry business.industry Organic Chemistry Co-processing engineering.material 010402 general chemistry 01 natural sciences 0104 chemical sciences Coating SCALE-UP engineering Physical and Theoretical Chemistry Process engineering business
Zdroj:	Organic Process Research & Development. 23:2685-2698
ISSN:	1520-586X 1083-6160
DOI:	10.1021/acs.oprd.9b00354
Popis:	Many active pharmaceutical ingredients (APIs) display poor powder properties and cannot be directly compressed into tablets with sufficient strength. The desired powder properties are often difficu...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5204be0aac0cf126fe229477d88e6003 https://doi.org/10.1021/acs.oprd.9b00354 Zobrazit plný text záznamu