Sea-blue histiocytosis and pancytopaenia associated with chronic total parenteral nutrition administration
| Autor: | M. Greaves, H. Baden, D.J. Meiklejohn |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Hepatosplenomegaly Sea-blue histiocytosis Hematology medicine.disease Short bowel syndrome Pancytopenia Gastroenterology Bone marrow examination Histiocytosis Parenteral nutrition Internal medicine Immunology medicine medicine.symptom business Histiocyte |
| Zdroj: | Clinical & Laboratory Haematology. 19:219-221 |
| ISSN: | 0141-9854 |
| DOI: | 10.1111/j.1365-2257.1997.tb00012.x |
| Popis: | A 22-year-old female on chronic total parenteral nutrition for short bowel syndrome presented for investigation of pancytopaenia and hepatosplenomegaly. Bone marrow examination revealed an infiltrate of sea-blue histiocytes and cytochemistry confirmed these to be lipid laden macrophages. The total amount of fat in the feeding regimen was subsequently reduced, and there has been a partial haematological improvement. The occurrence of sea-blue histiocyte syndrome complicating the fat emulsion component of chronic total parenteral nutrition has been reported recently. To our knowledge this report is the first where reduction in the lipid content of the feeding regimem has resulted in an improvement in the degree of pancytopaenia. |
| Databáze: | OpenAIRE |
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