Interferon production during interaction between lymphocytes and target L-cells in different phases of the mitotic cycle

Autor:	N. V. Leneva, B. M. Nemirovskaya
Rok vydání:	1980
Předmět:	Interferon production Immune system Interferon medicine Cytotoxic T cell General Medicine Cell cycle Biology Virology Molecular biology General Biochemistry Genetics and Molecular Biology Mitotic cycle medicine.drug
Zdroj:	Bulletin of Experimental Biology and Medicine. 89:351-353
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00834251
Popis:	Interferon is found in the culture medium after interaction between target L-cells synchronized (in the G1 and S) and unsynchronized with lymphocytes (intact, immune, and nonimmune, treated with actinomycin D). On interaction between immune lymphocytes and L-cells in the G1 phase, interferon production visibly commences after 30 min (25 units/ml), reaches a maximum after 10 h (75 units/ml), and then falls slightly to 48 h (65 units/ml). Interferon production during interaction between immune lymphocytes and L-cells in the G1 phase correlates with the cytotoxic action of the lymphocytes on these cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::51fa34c0089a4790a3f6f06b417d1c94 https://doi.org/10.1007/bf00834251 Zobrazit plný text záznamu Full text from SpringerLink