Méthylhalogénocyclopropanation des éthoxy-alcènes diversement alkylés. Identification stéréochimique des adduits et étude de la stéréosélectivité

Autor:	Raymond Le Goaller, Roger Barlet, Claude Gey
Rok vydání:	1982
Předmět:	chemistry.chemical_classification Steric effects Stereochemistry Organic Chemistry Salt (chemistry) General Chemistry Medicinal chemistry Catalysis Adduct Intermediate stage chemistry.chemical_compound 13c nmr spectroscopy chemistry Halogen Carbene Methyl iodide
Zdroj:	Canadian Journal of Chemistry. 60:1933-1941
ISSN:	1480-3291 0008-4042
DOI:	10.1139/v82-271
Popis:	Ethoxy-alkenes act as excellent carbene acceptors in the methylmonohalogenocyclopropanation reaction mediated by 1,1-dichloroethane and iodide-ion free methyl iodide. As well as chlorinated adducts, a large proportion of brominated products are obtained by means of halogen exchange at the carbene complex – salt intermediate stage. Adduct stereochemistry is determined by 1H and 13C nmr spectroscopy. The syn-stereoselectivity of the reaction is discussed in electronic and steric terms. [Journal Translation]
Databáze:	OpenAIRE
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