Tensile and biocompatibility properties of synthesized nano-hydroxyapatite reinforced ultrahigh molecular weight polyethylene nanocomposite
| Autor: | Alireza Khavandi, Seyed Ali Mirsalehi, Shamsodin Mirdamadi, Mohammadali Sattari, Mohammad Reza Naimi-Jamal |
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| Rok vydání: | 2015 |
| Předmět: |
Materials science
Nanocomposite Biocompatibility Scanning electron microscope Mechanical Engineering Composite number technology industry and agriculture Compression molding Osteoblast 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences medicine.anatomical_structure Mechanics of Materials Ultimate tensile strength Materials Chemistry Ceramics and Composites medicine Composite material 0210 nano-technology Tensile testing |
| Zdroj: | Journal of Composite Materials. 50:1725-1737 |
| ISSN: | 1530-793X 0021-9983 |
| Popis: | Ultrahigh molecular weight polyethylene–based nanocomposites reinforced with nano-sized hydroxyapatite particles were fabricated using internal mixer and compression molding with different weight percent of the nano-hydroxyapatite. In this study, first, hydroxyapatite nanoparticles were synthesized by sol–gel. Then, the mechanical and biological properties of nanocomposites were studied by tensile test and proliferation and cell adhesion assays using MG-63 osteoblast cells, respectively. Results of the tensile test showed that incorporation of 50 wt% nano-hydroxyapatite led to a 345.64% and 57.58% increase in Young's modulus and yield strength (compared to the pure ultrahigh molecular weight polyethylene), respectively. The effect of the nano-hydroxyapatite powders on the MG-63 osteoblast cells behavior was compared to those of a composite (positive control) and a negative control samples. Scanning electron microscopy micrographs revealed that cell–biomaterial interaction was carried out on the surface of the nanocomposites with normal phenotypic shape. Results of MTT assay exhibited that all samples are biocompatible. |
| Databáze: | OpenAIRE |
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