Human Antibody Responses Against Schistosomal Antigens

Autor:	Daniel G. Colley, Giovanni Gazzinelli, Iramaya R. C. Viana, Luci M. S. Dusse, Rodrigo Correa-Oliveira, Omar dos Santos Carvalho
Rok vydání:	1988
Předmět:	biology Helminthiasis Schistosomiasis medicine.disease biology.organism_classification Infectious Diseases Ancylostoma Antigen Virology Ascariasis Hookworm Infections parasitic diseases Immunology medicine Parasitology Schistosoma mansoni Ascaris lumbricoides
Zdroj:	The American Journal of Tropical Medicine and Hygiene. 38:348-355
ISSN:	1476-1645 0002-9637
Popis:	Sera of patients with either hookworm infections or ascariasis, who are from areas nonendemic for Schistosoma mansoni, contain antibody reactivity against extracts of S. mansoni schistosomula. Such patients with hookworm, but not those with Ascaris lumbricoides, also express considerable antibody activity against intact schistosomula and schistosomular membrane preparations. Sera from patients with schistosomiasis mansoni also contain these activities. Because these three helminthic infections often occur in the same areas, and concomitantly in patients, anti-schistosomular reactivity should not be ascribed only to exposure to schistosomes. The demonstration and definition of these surface-specific cross-reactivities point out the problems of serodiagnosis, and the potential of interactive influences in the common occurrence of multiple helminthic infections in humans.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::51d5d591f2d16b6f7a094e652266c364 https://doi.org/10.4269/ajtmh.1988.38.348 Zobrazit plný text záznamu