Acid-catalyzed cyclization of cembrene and isocembrol

Autor:	W. E. Thiessen, J. P. Hubbell, William G. Dauben, P. Oberhansli
Rok vydání:	1979
Předmět:	Chemical kinetics chemistry.chemical_compound chemistry Organic Chemistry Aromatization Organic chemistry Diterpene Ring (chemistry) Resonance (chemistry) Chemical reaction Medicinal chemistry Isomerization Catalysis
Zdroj:	The Journal of Organic Chemistry. 44:669-673
ISSN:	1520-6904 0022-3263
DOI:	10.1021/jo01319a001
Popis:	The acid-catalyzed ring closure of cembrene, a 14-membered ring diterpene, and its derivatives have been studied. The predominant reaction pathway yields a hydrophenanthrene ring system. Under mild conditions isomeric tricyclic compounds are formed, but under more forcing conditions aromatization of a ring occurs. The detailed mechanisms of these reaction processes have been evaluated. 1 figure, 3 tables.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::51baa672e2d406f485c897fba1ade9f2 https://doi.org/10.1021/jo01319a001 Zobrazit plný text záznamu