| Autor: |
Joseph K. Mwatha, Jane N. Mugwe, Michael M. Gicheru |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
LIFE: International Journal of Health and Life-Sciences. 5:105-118 |
| ISSN: |
2454-5872 |
| DOI: |
10.20319/lijhls.2019.51.105118 |
| Popis: |
Introduction: This study sought to identify circulatory cytokines and hematological profiles measureable in blood plasma in newly diagnosed HIV patients as possible biomarkers that could predict the progression of HIV and AIDS disease in the course of acute HIV infection. Methodology: A prospective cross sectional study design was used to recruit the participants at the Nakuru Provincial General hospital in Kenya. The study group included those who were HIV positive before and after commencing therapy and those who were HIV negative. The study group composed of male and female of different ages ranging from 7-72 years. Hematology auto analyzer system was used to analyze hematological parameters and indices. Types and concentrations of cytokines were determined using multiplex cytokine immunoassay by flow cytometry using Becton and Dickinsonfluorescence activated cell sorter (BD FACS) count. Descriptive statistics were applied and a p- value < 0.05 was considered statistically significant. Results: This study found a significant difference in mean Interleukin 12p70 (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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