Broadening the Factor V Leiden Paradox: Pulmonary Embolism and Multisystemic Arterial Thrombosis as 2 Sides of the Spectrum

Autor:	L Rachid, R Zerhoudi, M El Jamili, S l Karimi, M El Hattaoui
Rok vydání:	2022
Předmět:	hemic and lymphatic diseases cardiovascular diseases General Medicine
Zdroj:	Scholars Journal of Applied Medical Sciences. 10:630-634
ISSN:	2320-6691 2347-954X
DOI:	10.36347/sjams.2022.v10i04.033
Popis:	Factor V Leiden mutation is an inherited disorder of coagulation. Factor V Leiden resists the effects of activated protein C, so it takes longer to turn off Factor V Leiden. As a result, clotting goes on longer than usual. It’s associated with thrombotic events that classically involve the venous thrombosis and rarely arteries. However, the role of factor V Leiden in the genesis of arterial thrombosis is not yet fully understood. We report a case of a young woman with multiple thromboembolic events including pulmonary embolism, renal associated to hepatic infarction, apical thrombus on the left ventricle and ischemic stroke, in the context of a factor V mutation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5198d57c213522442cec3c01cf8abd99 https://doi.org/10.36347/sjams.2022.v10i04.033 Zobrazit plný text záznamu