Acute Abdomen from Kayexalate Utilization
| Autor: | Tu Tran Hyunh, Shotaro Sano, Jaime Te, Mehulkumar Joshi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Constipation Hyperkalemia business.industry medicine.medical_treatment nutritional and metabolic diseases Cathartic Enema urologic and male genital diseases Gastroenterology Surgery End stage renal disease Acute abdomen Internal medicine medicine medicine.symptom business Sodium Polystyrene Sulfonate Complication |
| Zdroj: | Journal of Clinical Case Reports. 6 |
| ISSN: | 2165-7920 |
| DOI: | 10.4172/2165-7920.1000889 |
| Popis: | Hyperkalemia in end stage renal disease patients is a common complication. Sodium polystyrene sulfonate (Kayexalate) is a commonly used in the treatment of hyperkalemia. This case report discusses about Kayexalateinduced colonic necrosis, a rare but fatal complication of this commonly used medication. Keywords Sodium polystyrene sulfonate; Kayexalate; Bowel; Necrosis; Acute abdomen Introduction Sodium polystyrene sulfonate (SPS, Kayexalate), has been used in management of hyperkalemia since 1957 when it was first discovered. Kayexalate is a cation resin used either as oral or as an enema form in the management of hyperkalemia. Originally sorbitol was mixed with sodium polystyrene sulfonate as a cathartic to avoid constipation. Even though kayexalate is used often to treat hyperkalemia, its side effect of colonic necrosis is a rare complication that was first discussed in 1987, in a series featuring five uremic patients. The study led to the FDA advisory to discontinue the addition of sorbitol due to this associated risk of colonic necrosis [1]. |
| Databáze: | OpenAIRE |
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