Modern Conservative Etiopathogenetic Treatment of Cervical Intraepithelial Neoplasia (literature review)

Autor: Valeriy Garbuziuk, Alla Binkovska, Anelia Shatkovska, Alla Kondratiuk, Larysa Dudikova, Anatoliy Hryhorenko, Olha Horbatiuk, Olena Herich
Rok vydání: 2020
Předmět:
Zdroj: Reports of Vinnytsia National Medical University. 24:332-338
ISSN: 2522-9354
1817-7883
DOI: 10.31393/reports-vnmedical-2020-24(2)-23
Popis: Annotation. We used PubMed, Cochrane Library, Google Scholar databases, mostly referring to publications from the last five years (2016–2020). The long-term persistence of oncogenic types of human papilloma virus is the main etiological factor for cervical intraepithelial neoplasia (CIN). Prolonged persistence of herpes infection can also have a transformative effect on cervical epithelium. Since this pathology is most often diagnosed in women of reproductive age, the maximum preservation of reproductive function, prevention of perinatal complications requires the search for new conservative CIN treatments aimed at the complete elimination of viruses and neoplastic cells. The effectiveness of conservative antiviral therapy of CIN I, II without the use of surgical methods has been proved, especially in women who have not fulfilled their reproductive plans. In addition, antiviral therapy during pre- and postoperative periods contributes to the reduction of complications and relapses in women with severe cervical neoplasia.
Databáze: OpenAIRE