Synthesis, antimicrobial and cytostatic activities of some derivatives of indolo[2,3-b]-1,5-benzothiazepine, a novel heterocyclic ring system

Autor:	A. Furlani, Luana Perioli, A. Papaioannou, L. Tuttobello, Vito Scarcia, Giuliano Grandolini, Valeria Ambrogi
Rok vydání:	1993
Předmět:	Pharmacology chemistry.chemical_compound biology chemistry Stereochemistry Organic Chemistry Drug Discovery Lactam General Medicine Ring (chemistry) Antimicrobial biology.organism_classification Bacteria
Zdroj:	European Journal of Medicinal Chemistry. 28:659-667
ISSN:	0223-5234
DOI:	10.1016/0223-5234(93)90024-9
Popis:	Some derivatives of indolo[2,3- b ]-1,5-benzothiazepine, a novel heterocyclic ring system, and of its 5,6-dihydroderivative have been obtained by Fischer indolization of corresponding phenylhydrazones. All the tetracyclic compounds were studied for their antimicrobial and cytostatic activities and several of them showed good activity against Gram-positive bacteria and Cryptococci .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::517be74c8ab39e45665bae86fc1c705b https://doi.org/10.1016/0223-5234(93)90024-9 Zobrazit plný text záznamu