Aortic Root Dilation and Testosterone Use: Are They Associated?
| Autor: | Luke Henderson, Benyam Goitom, James D. Grant, Nicola D'Attellis, Dominic Emerson, DeSean Thom |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Aorta business.industry Testosterone (patch) 030204 cardiovascular system & hematology medicine.disease Thoracic aortic aneurysm 03 medical and health sciences 0302 clinical medicine Anesthesiology and Pain Medicine Clinical research 030202 anesthesiology Internal medicine medicine.artery cardiovascular system medicine Cardiology Animal studies Cardiology and Cardiovascular Medicine business Aortic root dilation Dilated aortic root Young male |
| Zdroj: | Journal of Cardiothoracic and Vascular Anesthesia. 34:3395-3397 |
| ISSN: | 1053-0770 |
| DOI: | 10.1053/j.jvca.2020.05.003 |
| Popis: | Aortic root dilation and thoracic aortic aneurysms are relatively rare in young and healthy patient populations. However, a number of observed incidental cases regarding young males and testosterone use raises suspicion of a potential risk factor for aortic root dilation. The authors’ patient, a healthy 40-year-old man with a significant history of testosterone use who developed a massively dilated aortic root, is sufficiently alarming to report. Notwithstanding anecdotal cases, there exists a well-known association between elite strength athletes and aortic root dilation. Nevertheless, very little clinical research exists on the relationship between testosterone use and aortic root dilation and/or thoracic aortic aneurysms. Furthermore, a small number of animal studies showed a relationship between testosterone and vascular dilation, particularly the aorta. Although testosterone may play a role in the development of aortic pathologies, further research is necessary to clarify the possible relationship if cases such as these are to be prevented. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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