Polypharmacy Is Associated with Frailty, Nutritional Risk and Chronic Disease in Chilean Older Adults: Remarks from PIEI-ES Study

Autor: Sergio Wehinger, Alvaro Cerda, Marcelo Alarcón, Diego Arauna, Diego Méndez, José Francisco García-García, Eduardo Fuentes, Iván Palomo, Felipe Castro
Rok vydání: 2020
Předmět:
Zdroj: Clinical Interventions in Aging. 15:1013-1022
ISSN: 1178-1998
DOI: 10.2147/cia.s247444
Popis: Aim To analyze the relationship between polypharmacy and variables as frailty and other chronic comorbidities in Chilean older adults. Design Cross-sectional study. Participants One thousand two hundred and five older adults aged 65 and older. Methods The presence or absence of frailty syndrome was determined according to Fried criteria. Data collection was made through questionnaires conducted by an interview. Results The prevalence of polypharmacy was 37.59%. The prevalence of hyperpolypharmacy was 2%. Increased prevalence of frailty was demonstrated regarding the progression of the state of polypharmacy. When analyzing the contribution of frailty respect polypharmacy condition, frail state, nutritional risk and obesity are founded as a factor associated with polypharmacy. Regarding chronic disease, hypertension (OR: 8.039, p
Databáze: OpenAIRE