Two New Polyketides from Mangrove Endophytic Fungus Dothiorella sp

Autor: Xi-Ping Du, Wen-Jin Su
Rok vydání: 2014
Předmět:
Zdroj: Chemistry of Natural Compounds. 50:214-216
ISSN: 1573-8388
0009-3130
DOI: 10.1007/s10600-014-0915-y
Popis: Two new polyketides, named dothiorelones F (2) and I (3), as well as three known analogues (dothiorelones E (1), G (4), and H (5)) have been isolated from the mangrove endophytic fungus Dothiorella sp. Their structures were elucidated on the basis of NMR data and mass spectrometry. Dothiorelones F (2) and G (4) showed significant cytotoxicity against Raji cancer cell line with IC50 values 2 μg/mL.
Databáze: OpenAIRE