Biofilm Resistant Surfaces and Coatings on Implants: A Review
| Autor: | P S V V S Narayana, P S V V Srihari |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
010302 applied physics
Biocompatibility biology Chemistry medicine.drug_class Antibiotics Biofilm 02 engineering and technology biochemical phenomena metabolism and nutrition Surface engineering 021001 nanoscience & nanotechnology biology.organism_classification Antimicrobial 01 natural sciences Microbiology Surface coating 0103 physical sciences medicine Surface modification 0210 nano-technology Bacteria |
| Zdroj: | Materials Today: Proceedings. 18:4847-4853 |
| ISSN: | 2214-7853 |
| DOI: | 10.1016/j.matpr.2019.07.475 |
| Popis: | The study of microbes in and around us that have a drastic affect on human health plays a vital role in medicine. Bacterial infections kill millions of people in the world. The structured formation of bacterial communities, known as biofilms, is the major cause of bacterial infections. Nosocomial infections are caused by biofilms due to their pathogenic nature. Biofilms contribute about 80% and 65% to chronic and microbial infections respectively. The adhesion of bacteria to implant surface is the source of biofilm formation. Therefore, the surface characteristics of the implant material dictate the host cells association and response. Biofilms are resistant to antibiotics, disinfectants, and the human immune system. Implants surface modifications play a vital role in improving their biocompatibility and anti-infection properties. Providing antibacterial and adhesion resistant surface coating acts as a novel approach to combat biofilms. This review presents the process of biofilm formation on different implants and the next generation of surface modification techniques to enhance biocompatibility and antimicrobial functionality using surface engineering and nanobiotechnology.. |
| Databáze: | OpenAIRE |
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