Photodynamic Action Of Benzochlorins
| Autor: | Steven H. Selman, Greta M. Garbo, Ashraf Rampersaud, Rick W. Keck, Dimitris Skalkos, Alan R. Morgan |
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| Rok vydání: | 1989 |
| Předmět: | |
| Zdroj: | SPIE Proceedings. |
| ISSN: | 0277-786X |
| DOI: | 10.1117/12.978015 |
| Popis: | A series of benzochlorins have been prepared and tested for tumoricidal activity using the FANFT-induced rat bladder tumor model. Results indicate that these chlorin derivatives, in combination with red light, can cause significant tumor regression at doses as low as 0.5 - 1.0 mg/kg body weight. This compares favorably with other sensitizers tested in the same model and suggests that further studies on the effectiveness of benzochlorins in photodynamic therapy be performed. |
| Databáze: | OpenAIRE |
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