Experimental Studies of the Efficacy of Transmyocardial Laser Revascularization Using an Erbium Laser
| Autor: | Yu. K. Danyleiko, Stepan N Andreev, B. I. Denker, S. V. Belov, A. V. Molochkov, I. V. Zhbanov, A. B. Egorov, E. G. Osmanov, V. A. Salyuk |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Ischemic myocardium business.industry 0206 medical engineering Biomedical Engineering Medicine (miscellaneous) 02 engineering and technology Laser 020601 biomedical engineering Chronic ischemic heart disease law.invention Medical Laboratory Technology medicine.anatomical_structure Animal model Erbium laser law Internal medicine medicine Cardiology In patient Transmyocardial laser revascularization cardiovascular diseases business Artery |
| Zdroj: | Biomedical Engineering. 52:224-230 |
| ISSN: | 1573-8256 0006-3398 |
| Popis: | Results obtained using an erbium laser to produce directed angiogenesis in transmyocardial laser revascularization in experiments using an animal model of chronically ischemic myocardium are presented. An assessment of the efficacy of using the erbium laser to produce targeted angiogenesis is presented. The optimum operating regimes for erbium laser pulse irradiation of the myocardium, taking account of thermal tissue lesions, are identified. Morphological changes are investigated and morphometric analysis in tissues in the area of the transmyocardial laser channels are analyzed in a model of chronic ischemic heart disease (IHD) in dogs. Studies were performed for subsequent development and introduction of the new method into clinical practice in patients with IHD with diffuse coronary artery lesions. |
| Databáze: | OpenAIRE |
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