Unique DNA-barcoded aerosol test particles for studying aerosol transport
| Autor: | Sara B. Hall, Edwin Herchert, Vicente R. Tur-Rojas, James A. Day, George R. Farquar, Ruth N. Harding, A. Daniel Jones, Elizabeth A. Vitalis, Cynthia B. Thomas, Elizabeth K. Wheeler, Richard Yoder, Trond Jorgensen, Christine A. Hara |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Range (particle radiation) Particle properties Air transport 030106 microbiology Nanotechnology Pollution Aerosol 03 medical and health sciences Test material Synthetic DNA Environmental Chemistry Environmental science General Materials Science National laboratory Transport studies |
| Zdroj: | Aerosol Science and Technology. 50:429-435 |
| ISSN: | 1521-7388 0278-6826 |
| Popis: | Data are presented for the first use of novel DNA-barcoded aerosol test particles that have been developed to track the fate of airborne contaminants in populated environments. Until DNATrax (DNA Tagged Reagents for Aerosol eXperiments) particles were developed, there was no way to rapidly validate air transport models with realistic particles in the respirable range of 1–10 μm in diameter. The DNATrax particles, developed at Lawrence Livermore National Laboratory (LLNL) and tested with the assistance of the Pentagon Force Protection Agency, are the first safe and effective materials for aerosol transport studies that are identified by DNA molecules. The use of unique synthetic DNA barcodes overcomes the challenges of discerning the test material from pre-existing environmental or background contaminants (either naturally occurring or previously released). The DNATrax particle properties are demonstrated to have appropriate size range (approximately 1–4.5 μm in diameter) to accurately simulate bac... |
| Databáze: | OpenAIRE |
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