Citriperazines A-D produced by a marine algae-derived fungus Penicillium sp. KMM 4672
| Autor: | Dmitry V Berdyshev, Gunhild von Amsberg, O. F. Smetanina, Yuliya V. Khudyakova, Anton B. Rasin, Shamil Sh. Afiyatullov, Olesya I Zhuravleva, A. N. Yurchenko, Roman S. Popov, Elena V Ivanets, Sergey A. Dyshlovoy |
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| Rok vydání: | 2019 |
| Předmět: |
biology
010405 organic chemistry Chemistry Stereochemistry Organic Chemistry Plant Science Fungus Penicillium sp. KMM 4672 biology.organism_classification 01 natural sciences Biochemistry Human prostate 0104 chemical sciences Analytical Chemistry 010404 medicinal & biomolecular chemistry Algae Penicillium Cytotoxicity Diketopiperazines |
| Zdroj: | Natural Product Research. 34:1118-1123 |
| ISSN: | 1478-6427 1478-6419 |
| Popis: | Four new diketopiperazine alkaloids, citriperazines A-D were isolated from algae-derived Penicillium sp. KMM 4672. The structures of compounds 1-4 were determined using spectroscopic methods. The absolute configurations of compounds 1 and 4 were established by comparison of calculated and experimental ECD spectra. The cytotoxicity of compounds 1-4 against several human prostate cell lines was evaluated. |
| Databáze: | OpenAIRE |
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