Welwitschiilactone A, B and C, three new 30-norfriedelane triterpenes from the roots of Caloncoba welwitschii (Oliv.) Gilg (Achariaceae)
| Autor: | Jean Duplex Wansi, Jean Claude Ndom, Chimène Victoire Tchamadeu Keugwa, Alain François Kamdem Waffo, Jules Lobe Songue, Alain Tadjong Tcho |
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| Rok vydání: | 2018 |
| Předmět: |
biology
010405 organic chemistry Stereochemistry Chemistry Plant composition Plant Science biology.organism_classification 01 natural sciences Biochemistry Achariaceae 0104 chemical sciences Terpene 010404 medicinal & biomolecular chemistry Triterpenoid Agronomy and Crop Science Chemical composition Two-dimensional nuclear magnetic resonance spectroscopy Caloncoba welwitschii Biotechnology |
| Zdroj: | Phytochemistry Letters. 27:15-19 |
| ISSN: | 1874-3900 |
| DOI: | 10.1016/j.phytol.2018.06.011 |
| Popis: | Three new 30-norfriedelane triterpenoids named, 3β,21β-dihydroxy-27-oxo-30-nor-(D:A)-friedo-olean-20(29)-en-27,19α-lactone (welwitschiilactone A) (1), 21β-hydroxy-3,27-dioxo-30-nor-(D:A)-friedo-olean-20(29)-en-27,19α-lactone (welwitschiilactone B) (2) and 2β,21β-dihydroxy-27-oxo-30-nor-(D:A)-friedo-olean-20(29)-en-27,19α-lactone (welwitschiilactone C) (3) along with seven known compounds were isolated from the methanol extract of the roots of Caloncoba welwitschii. Their structures were determined by comprehensive spectroscopic analyses (1D and 2D NMR, EI-, ESI- and HRESI-MS). The relative configuration of the 19-oxymethine and the 21-hydroxy have been established by using the NOESY spectrum. |
| Databáze: | OpenAIRE |
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