Fluorescence switching of photochromic vinylpyrene-substituted 2′-deoxyguanosine

Autor:	Yoshio Saito, Katsuhiko Matsumoto, Takashi Morii, Yoshiki Takeuchi, Subhendu Sekhar Bag, Isao Saito, Satoshi Kodate
Rok vydání:	2009
Předmět:	Organic Chemistry Photochemistry Biochemistry Fluorescence Fluorescence spectroscopy chemistry.chemical_compound Photochromism chemistry Resonance fluorescence Drug Discovery Deoxyguanosine Irradiation Isomerization Visible spectrum
Zdroj:	Tetrahedron Letters. 50:1403-1406
ISSN:	0040-4039
Popis:	We synthesized C8-vinylpyrene-substituted 2′-deoxyguanosine VPyG and studied the photoregulated reversible E–Z isomerization. When E-isomer was irradiated with visible light (>420 nm), E- to Z-isomerization took place very rapidly, while upon irradiation with UV-light (∼365 nm), Z-isomer was converted to E-isomer. When Z-isomer was illuminated with 365–400 nm light, no fluorescence was observed, while E-isomer showed a very strong fluorescence emission, indicating that VPyG could be a useful fluorescence switching molecule.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::513278328fd1cddffcf448ba39d3545d https://doi.org/10.1016/j.tetlet.2009.01.029 Zobrazit plný text záznamu Full Text from ScienceDirect