Dyslipidemia and other cardiovascular risk factors in relation to manifest cardiovascular disease in patients with chronic obstructive pulmonary disease in the Canary Islands

Autor: A. Afonso Díaz, M.A. García Bello, J.M. Figueira Gonçalves, N. Bethencourt Martín, M.D. Martín Martínez, D. Díaz Pérez, J. Mesa Fumero, I. García-Talavera, S. García Hernández
Rok vydání: 2020
Předmět:
Zdroj: Revista Clínica Española (English Edition). 220:267-274
ISSN: 2254-8874
DOI: 10.1016/j.rceng.2019.05.011
Popis: Background Cardiovascular disease has a negative impact on the vital prognosis of patients with chronic obstructive pulmonary disease (COPD), where dyslipidaemia (DLP) and arterial hypertension (AHT) are considered the most prevalent risk factors. The objective of this study was 1) to assess the relationship between diagnosed DLP and cardiovascular disease in COPD patients and compare it with other known cardiovascular risk factors and 2) to determine the relationship between the different cardiovascular comorbidities and the severity groups according to the GOLD 2017 classification. Methods A cross-sectional, observational study was performed in 454 outpatients with COPD during their follow up. We calculated the prevalence of each of the cardiovascular comorbidities and the probability of each of the cardiovascular risk factors to occur jointly with a vascular disease (RRij). Results A total of 66.7% of the patients had DLP, whereby DLP was related to cerebrovascular accidents (CVA) (RRij 1.36, p = 0.0054), chronic kidney disease (CKD) (RRij 1.34, p = 0.00023), and peripheral arterial disease (PAD) (RRij 1.38, p = 0.00015). AHT was mostly related to CVA (RRij 1.41, p = 0.0014) and CKD (RRij 1.42, p Conclusion DLP was related to CVA, CKD, and PAD. AHT and T2DM are the conditions that mostly relate to HF and CVA.
Databáze: OpenAIRE
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