Separation of nicotine metabolites by capillary zone electrophoresis and capillary zone electrophoresis/mass spectrometry

Autor:	R. F. Smith, K. Chambers, L. W. Tetler, M. E. Palmer
Rok vydání:	2001
Předmět:	Analyte Chromatography Chemistry Organic Chemistry Analytical chemistry Ms analysis Mass spectrometry Mass spectrometric Capillary electrophoresis–mass spectrometry Analytical Chemistry Nicotine Capillary electrophoresis medicine Spectroscopy medicine.drug
Zdroj:	Rapid Communications in Mass Spectrometry. 15:224-231
ISSN:	1097-0231 0951-4198
DOI:	10.1002/1097-0231(20010215)15:3<224::aid-rcm213>3.0.co;2-z
Popis:	The use of capillary zone electrophoresis (CZE) and capillary zone electrophoresis/mass spectrometry (CZE/MS) has been demonstrated, in principle, for the separation of nicotine and nicotine metabolites. The buffer system developed for separation and detection by CZE/UV was modified for use in CZE/MS analysis. Several of the metabolites are isobaric and tandem mass spectrometric (MS/MS) techniques have been used to differentiate such analytes.
Databáze:	OpenAIRE
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