Mn–Fe layered double hydroxide nanosheets: a new photothermal nanocarrier for O2-evolving phototherapy
Autor: | Chao Wang, Yudi Ruan, Wenyao Zhen, Xiaodai Jia, Xiue Jiang |
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Rok vydání: | 2018 |
Předmět: |
Hyperthermia
medicine.medical_treatment Photodynamic therapy 02 engineering and technology 010402 general chemistry 01 natural sciences Catalysis chemistry.chemical_compound Materials Chemistry medicine Photosensitizer Tumor hypoxia Chemistry Metals and Alloys General Chemistry Photothermal therapy 021001 nanoscience & nanotechnology medicine.disease Tumor tissue 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Ceramics and Composites Biophysics Hydroxide Nanocarriers 0210 nano-technology |
Zdroj: | Chemical Communications. 54:11729-11732 |
ISSN: | 1364-548X 1359-7345 |
Popis: | Iron–manganese layered double hydroxide nanosheets were developed as an effective photothermal nanocarrier for loading a photosensitizer. The catalase-like activity enables the nanosheets to decompose H2O2 into O2, overcoming tumor hypoxia and enhancing O2-dependent photodynamic therapy (PDT). The combination of PDT and photothermal therapy (PTT) can almost completely eliminate tumor tissues. |
Databáze: | OpenAIRE |
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