Identification of Small-Molecule Inhibitors of the Salmonella FraB Deglycase Using a Live-Cell Assay
| Autor: | Anice Sabag-Daigle, Erin F. Boulanger, Pankajavalli Thirugnanasambantham, Jamison D. Law, Alex J. Bogard, Edward J. Behrman, Venkat Gopalan, Brian M. M. Ahmer |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Microbiology Spectrum. 11 |
| ISSN: | 2165-0497 |
| Popis: | Nontyphoidal salmonellosis is a serious threat in the United States and globally. We have recently identified an enzyme, FraB, that when mutated renders Salmonella growth defective in vitro and unfit in mouse models of gastroenteritis. |
| Databáze: | OpenAIRE |
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