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Acta Obstet Gynecol Scand 2002; 81: 252-257. © Acta Obstet Gynecol Scand 2002 Background. To compare the efficacy and complications of intravaginal misoprostol application with oxytocin infusion for induction of labor in toxemia of pregnancy with a modified Bishop score of ≤4. Methods. A hundred preeclamptic women with a modified Bishop score of ≤4 were randomized into two groups of 50 patients one group receiving 50 μg intravaginal misoprostol 4 times at 4 hour intervals, the second group receiving oxytocin infusion for induction of labor starting from 1 mIU/per minute, increasing it every 30 minutes with 2 mIU/per minute increments up to maximum of 30 mIU/per minute. Modified Bishop scores 12 hours after induction, the time from induction to delivery, the route of delivery, fetal outcome and maternal complications were recorded. Statistical analyses were performed using Mann Whitney-U, Chi-Square and hypothesis tests about differences for two proportions ( t test) to determine differences between the tw... |