Forces at individual pseudopod-filament adhesive contacts

Autor:	Sean P. McBride, Bruce M. Law, Bret N. Flanders, Prem S. Thapa, David Moore-Nichols, Govind Paneru
Rok vydání:	2011
Předmět:	Protein filament Cantilever Materials science Physics and Astronomy (miscellaneous) Nanotechnology Pseudopodia macromolecular substances Adhesion Adhesive Spring (mathematics) Composite material Force sensor Cellular biophysics
Zdroj:	Applied Physics Letters. 99:093702
ISSN:	1077-3118 0003-6951
DOI:	10.1063/1.3628454
Popis:	On-chip cellular force sensors are fabricated from cantilever poly(3,4-ethylene dioxythiophene) filaments that visibly deflect under forces exerted at individual pseudopod-filament adhesive contacts. The shape of the deflected filaments and their ∼3 nN/μm spring constants are predicted by cantilever rod theory. Pulling forces exerted by Dictyostelium discoideum cells at these contacts are observed to reach ∼20 nN without breaking the contact.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::50cbae1ea4778beaab90d566080d7f8f https://doi.org/10.1063/1.3628454 Zobrazit plný text záznamu