Is There Any Effect of Addition of Hyperbaric Oxygen or Intratympanic Steroid to Systemic Steroids in Idiopathic Sudden Sensorineural Hearing Loss Treatment?
| Autor: | Kemal Keseroglu, Ömer Bayır, Ahmet Uluat, Güleser Saylam, Emel Çadalli Tatar, Mehmet Hakan Korkmaz, Ali Özdek, Gökhan Toptaş |
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| Rok vydání: | 2020 |
| Předmět: |
0303 health sciences
030306 microbiology Systemic steroid business.industry medicine.medical_treatment Salvage treatment Significant difference General Medicine Long term results 030204 cardiovascular system & hematology medicine.disease Steroid Clinical trial 03 medical and health sciences 0302 clinical medicine Hyperbaric oxygen Anesthesia Medicine Sensorineural hearing loss business |
| Zdroj: | TURKISH JOURNAL OF MEDICAL SCIENCES. |
| ISSN: | 1303-6165 |
| Popis: | Background/aim This study aims to determine the therapeutic superiority of the addition of intratympanic steroid or hyperbaric oxygen therapy to systemic steroid treatment in idiopathic sudden sensorineural hearing loss as initial treatment, and evaluate the long- term results of salvage treatment. Materials and methods This study was a retrospective clinical trial with a total of 96 patients with idiopathic sudden sensorineural hearing loss. Patients were divided into 3 groups. Group 1 (n: 32) received systemic steroid treatment. Group 2 (n: 32) received the Group 1 protocol plus intratympanic steroid treatment. Group 3 (n: 32) received the Group 1 protocol plus hyperbaric oxygen treatment. Pretreatment and postinitial audiologic evaluations were performed, and the hearing outcome was analyzed with Furuhashi criteria. All patients, except those who experienced total recovery after initial treatment, were directed to salvage treatment. Audiologic assessment was performed again after salvage treatment and a mean follow-up period of 36.5 months. Results Each group was homogenous according to demographics, audiologic data, and prognostic factors. There was no statistically significant difference in recovery and success rate within the 3 groups after initial treatment. (P: 0.66, P: 0.248, respectively). Successful results were obtained after salvage treatment in only 3 patients (5%). These patients received follow-up treatment at a mean of 36.5 months, but there was no spontaneous recovery after the end of salvage treatment. Conclusion The addition of intratympanic steroids or hyperbaric oxygen to systemic steroids caused no significant hearing improvement as the initial treatment of idiopathic sudden sensorineural hearing loss. The efficacy of salvage treatment was limited, and there was no spontaneous hearing improvement after the long-term follow-up. |
| Databáze: | OpenAIRE |
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