Growth of a solitary pulmonary nodule after 6 years diagnosed as oncocytic carcinoid tumour with a high 18-fluorodeoxyglucose (18F-FDG) uptake in positron emission tomography-computed tomography (PET-CT)
| Autor: | Ozhan Ozdogan, Aydanur Kargi, Duygu Gürel, Onur Turan, Ahmet Önen, Can Sevinc |
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| Rok vydání: | 2012 |
| Předmět: |
Pulmonary and Respiratory Medicine
Fluorodeoxyglucose PET-CT Solitary pulmonary nodule medicine.medical_specialty business.industry Standardized uptake value medicine.disease Malignancy Pulmonary carcinoid tumour medicine Immunology and Allergy Carcinoid tumour Radiology business Genetics (clinical) Carcinoid syndrome medicine.drug |
| Zdroj: | The Clinical Respiratory Journal. 7:e1-e5 |
| ISSN: | 1752-6981 |
| DOI: | 10.1111/j.1752-699x.2011.00274.x |
| Popis: | Introduction: Pulmonary carcinoid tumour is low-grade neuroendocrine malignancy that is seen 1%–2% of all lung neoplasms. Oncocytic carcinoid type is a rarely seen variant of pulmonary carcinoids. As carcinoid tumours have hypometabolic activity, they usually have lower 18-fluorodeoxyglucose (18F-FDG) uptake than expected for lung carcinoma on positron emission tomography (PET). Case Report: A 45-year-old non-smoking man had a stable solitary pulmonary nodule followed for 6 years; the tumour remained the same size (1.5 × 2.4 cm) during this period. The patient was admitted to the hospital with complaints of repetitive sneezing and rhinorrhoea. He also experienced flushing and bronchospasm. His chest X-ray revealed a minimal increase in the size of the solitary pulmonary nodule (2.0 × 2.8 cm). In PET-computed tomography (CT), the parenchymal nodule in the anterior segment of the right lung had a standard uptake value of 38.0 mg/mL, which was interpreted as a malignant nodule. He underwent fibre-optic bronchoscopy, but cytology showed no evidence of malignancy. Right upper and middle bilobectomy was performed, and a pulmonary carcinoid tumour with an oncocytic subgroup was diagnosed. The diagnosis of carcinoid syndrome was further confirmed by an elevated 24-h urinary excretion of 5-hydroxyindoleacetic acid. Conclusion: We present a rare case of an oncocytic carcinoid tumour with an increase in the size of a solitary pulmonary nodule after 6 years' follow-up. In addition, PET-CT showed a very high 18F-FDG uptake in this patient, which is an unexpected finding with a pulmonary carcinoid tumour. Please cite this paper as: Turan O, Ozdogan O, Gurel D, Onen A, Kargi A and Sevinc C. Growth of a solitary pulmonary nodule after 6 years diagnosed as oncocytic carcinoid tumour with a high 18F-FDG uptake in positron emission tomography-computed tomography (PET-CT). Clin Respir J 2013; 7: e1–e5. |
| Databáze: | OpenAIRE |
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