Optimization of M2e cassette amino acid composition for the development of universal influenza vaccine
| Autor: | Daria А. Mezhenskaya, Irina N. Isakova-Sivak, Anastasiya E. Katelnikova, Larisa G. Rudenko |
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| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Medical academic journal. 21:127-130 |
| ISSN: | 2687-1378 1608-4101 |
| DOI: | 10.17816/maj76326 |
| Popis: | The development of a universal influenza vaccine with a wide spectrum and duration of action is one of the serious public health problems. This study is dedicated to optimization of an immunogen covering the M2e epitopes of influenza A viruses circulating in the natural reservoir, as well as the creation of a prototype of a universal influenza vaccine with subsequent quantitative and qualitative assessment of the induced anti-M2e responses in ferrets. |
| Databáze: | OpenAIRE |
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