A Combination approach using Areca nut and Ketoconazole for Treating Cutaneous Candidiasis
| Autor: | Adithya Chandrashekar, Manoj M Wagle, V. M. Subrahmanyam, Rajath Kanchan R, Kiran Noel Lobo |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Nut medicine.medical_specialty biology business.industry digestive oral and skin physiology biology.organism_classification Dermatology 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis medicine Pharmacology (medical) Ketoconazole Cutaneous candidiasis business Pharmacology Toxicology and Pharmaceutics (miscellaneous) Areca medicine.drug |
| Zdroj: | Research Journal of Pharmacy and Technology. :3074-3076 |
| ISSN: | 0974-360X 0974-3618 |
| DOI: | 10.52711/0974-360x.2021.00537 |
| Popis: | Fungal infections caused by Candida are often associated with increasing rates of morbidity and mortality. It is a serious concern for patients with immunocompromised system. The resistance to Ketoconazole, a known antifungal agent is increasing at an alarming rate and a number of such cases have been reported in the recent years. In order to circumvent this problem, a study was carried out using ketoconazole-areca nut (Areca catechu L.) combination. When this combination was tested against Candida albicans, there was an increase in the antifungal activity of ketoconazole. The study can be explored further for the design of suitable topical formulations containing the above combination in the treatment of cutaneous candidiasis. |
| Databáze: | OpenAIRE |
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