PREVALENCE, DISTRIBUTION AND DETERMINANTS OF ESCHERICHIA COLI RESISTANCE TO CEFTRIAXONE IN ADULT INDOOR UTI POPULATION OF DISTRICT PESHAWAR, PAKISTAN
| Autor: | Kiran Javed, Noor Ul Iman, Muhammad Asim Khan, Ubed Ullah, Imran Ullah |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
education.field_of_study Veterinary medicine Resistance (ecology) business.industry 030106 microbiology Population 030209 endocrinology & metabolism medicine.disease_cause 03 medical and health sciences 0302 clinical medicine medicine Ceftriaxone Distribution (pharmacology) business education Escherichia coli medicine.drug |
| Zdroj: | GJMS Vol 18, No.2, Apr-Jun 2020. 18:45-53 |
| ISSN: | 1997-2067 1819-7973 |
| Popis: | Background: Escherichia coliresistance to ceftriaxone in UTIs is an emerging health problem.Our objectives were to determine prevalence, distribution and determinants of E. coliresistance to ceftriaxone in adult indoor UTI population of District Peshawar, Pakistan. Materials & Methods:This cross-sectional study was conducted in Department of Medicine, Khyber Teaching Hospital, Peshawar, Pakistan from 1st January 2017 to 30th June 2017. 380 UTIs cases were selected from population at riskconsecutively.Sex and age groups were demographic, while presence of E. coli resistance to ceftriaxone was research variable. All variables were nominal.Prevalenceand distribution were analyzed by count, percentage and confidence intervals for proportion for population. Hypotheses for distribution were substantiated by chi-square goodness-of-fit and of association by chi-square test of association. Results: Out of 380 patients with UTI, 136 (35.80%) were men,244(64.20%) women, 262 (68.95%) in age group 18-45 years and 118 (31.05%) in age group 46-65 years. Frequency/ prevalence of E. coli resistance was 287/380 (75.53%, 95%CI 71.20-79.85). Out of 287 patients with E. coli resistance to ceftriaxone, 101 (26.58%) were men and 186 (48.95%) women, 198 (52.11%) in age group 18-45 years and 89 (23.42%) in age group 46-65 years. Our prevalence of E. coli resistance to ceftriaxone was higher than expected (p |
| Databáze: | OpenAIRE |
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