Structural determination of mannopeptimycin cyclic acetals

Autor:	Guy T. Carter, Xidong Feng, Bo Shen, Haiyin He, Ting-Zhong Wang, Joseph Ashcroft, Russell Dushin, Frank E. Koehn
Rok vydání:	2004
Předmět:	chemistry.chemical_compound Mannopeptimycin Chemistry Stereochemistry Organic Chemistry Drug Discovery Organic chemistry Mannose Biochemistry
Zdroj:	Tetrahedron Letters. 45:5889-5893
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2004.05.155
Popis:	In structure–activity relationship (SAR) studies on mannopeptimycin antibiotics, mannopeptimycin α( 1 ) was acetalized by reacting with certain dialkyl acetals under acidic conditions. The major products of these reactions were determined to be cyclic acetals at the 4,6-positions of the terminal mannose (Man-B), by exemplary spectroscopic analyses of two typical acetalization products 2 and 3 .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::50a9f8eb98e8df04e70bb7cfb5b64291 https://doi.org/10.1016/j.tetlet.2004.05.155 Zobrazit plný text záznamu Full Text from ScienceDirect