ChemInform Abstract: Palladium-Catalyzed Carbonylation Reactions of Aryl Bromides at Atmospheric Pressure: A General System Based on Xantphos

Autor:	Dominique M. M. Freckmann, Donald A. Watson, Stephen L. Buchwald, Timothy E. Barder, Joseph R. Martinelli
Rok vydání:	2009
Předmět:	chemistry.chemical_compound chemistry Atmospheric pressure Ligand Xantphos Aryl Polymer chemistry chemistry.chemical_element General Medicine Crystal structure Carbonylation Catalysis Palladium
Zdroj:	ChemInform. 40
ISSN:	1522-2667 0931-7597
Popis:	A method for the Pd-catalyzed carbonylation of aryl bromides has been developed using Xantphos as the ligand. This method is effective for the direct synthesis of Weinreb amides, 1° and 2° benzamides, and methyl esters from the corresponding aryl bromides at atmospheric pressure. In addition, a putative catalytic intermediate, (Xanphos)Pd(Br)benzoyl, was prepared and an X-ray crystal structure was obtained revealing an unusual cis-coordination mode of Xantphos in this palladium−acyl complex.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::5098316df00edce3ad901a0249ea4c8d https://doi.org/10.1002/chin.200905075 Zobrazit plný text záznamu Plný text