Reciprocal Changes in Serum Concentrations of 3,3′,5′-Triiodothyronine (Reverse T3) and 3,3′5-Triiodothyronine (T3) in Systemic Illnesses
| Autor: | Michael J. Reza, Inder J. Chopra, David H. Solomon, Usha Chopra, Stephen R. Smith |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
medicine.medical_specialty
Cirrhosis Triiodothyronine business.industry Endocrinology Diabetes and Metabolism Biochemistry (medical) Clinical Biochemistry Febrile illness Serum concentration medicine.disease Biochemistry Reverse triiodothyronine chemistry.chemical_compound Endocrinology chemistry Reverse t3 Internal medicine Severe protein calorie malnutrition Medicine In patient business |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 41:1043-1049 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-41-6-1043 |
| Popis: | Serum concentrations of 3,3′,5′-triiodothyronine (reverse T3, rT3) were measured in adult patients with several systemic illnesses whose serum total and/or free T3 were low, serum total T4 was low or normal, and free T4 was either normal or elevated. The mean serum rT3 was 76, 46, and 77 ng per 100 ml in patients with hepatic cirrhosis, chronic renal failure, and acute febrile illnesses, respectively; the values in patients with hepatic cirrhosis and acute febrile illness were significantly higher than, and values in patients with renal failure did not differ significantly from, the mean serum rT3 (41 ng per 100 ml) in normal subjects. The mean serum rT3 in another group of patients from Calcutta, India, who had severe protein calorie malnutrition (PCM), was 53 ng per 100 ml; it was significantly higher than the corresponding value, 22 ng per 100 ml, in the same patients after feeding treatment. Mean serum rT3 in patients with systemic illnesses was not so high as that (151 ng per 100 ml) in the normal ne... |
| Databáze: | OpenAIRE |
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