ChemInform Abstract: A Novel Stereo-controlled Nucleobase Exchange Process for the Synthesis of 2′-C-Branched Nucleosides
Autor: | Ian A. O'Neil, Volker Fehring, Richard Cosstick, Mai Yee Chan |
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Rok vydání: | 2010 |
Předmět: | |
Zdroj: | ChemInform. 32 |
ISSN: | 1522-2667 0931-7597 |
DOI: | 10.1002/chin.200107195 |
Popis: | A novel stereo-controlled process is described which enables the uracil base on a 2′-deoxy-2′-α-C-carboxymethyluridine nucleoside to be exchanged for either a purine or another pyrimidine base, via the intermediacy of an isolable pentofuranosyl butyrolactone. |
Databáze: | OpenAIRE |
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