ChemInform Abstract: A Novel Stereo-controlled Nucleobase Exchange Process for the Synthesis of 2′-C-Branched Nucleosides

Autor: Ian A. O'Neil, Volker Fehring, Richard Cosstick, Mai Yee Chan
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 32
ISSN: 1522-2667
0931-7597
DOI: 10.1002/chin.200107195
Popis: A novel stereo-controlled process is described which enables the uracil base on a 2′-deoxy-2′-α-C-carboxymethyluridine nucleoside to be exchanged for either a purine or another pyrimidine base, via the intermediacy of an isolable pentofuranosyl butyrolactone.
Databáze: OpenAIRE