Integrated optical input grating couplers as chemo- and immunosensors

Autor:	Ph. M. Nellen, W. Lukosz
Rok vydání:	1990
Předmět:	Adsorption Materials science Materials Chemistry Metals and Alloys Analytical chemistry Electrical and Electronic Engineering Grating Condensed Matter Physics Instrumentation Waveguide (optics) Human Immunoglobulin G Surfaces Coatings and Films Electronic Optical and Magnetic Materials
Zdroj:	Sensors and Actuators B: Chemical. 1:592-596
ISSN:	0925-4005
DOI:	10.1016/0925-4005(90)80280-d
Popis:	With an input grating coupler sensor, we investigated the immunobinding of an antibody (rabbit anti-h-IgG) to the antigen human immunoglobulin G (h-IgG), immobilized by adsorption on a SiO2-TiO2 waveguide surface. The feasibility of direct immunosensors and immunoassays for antibody concentrations down to c ≈ 1 × 10−9 mol/l was demonstrated. We also studied the response of the sensor to changes in salt concentration and pH value.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::50794253265877f02e9f9e2b83bf8f98 https://doi.org/10.1016/0925-4005(90)80280-d Zobrazit plný text záznamu