Electron microscopy study of skeletal muscle microvasculature in the paraneoplastic phenomenon
| Autor: | L. Sosa, A. Márquez, M. Correa, H.J. Finol, P. Tonino, Müller B |
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| Rok vydání: | 1996 |
| Předmět: | |
| Zdroj: | Proceedings, annual meeting, Electron Microscopy Society of America. 54:772-773 |
| ISSN: | 2690-1315 0424-8201 |
| DOI: | 10.1017/s0424820100166324 |
| Popis: | In addition to signs and symptoms at sites of primary and metastatic disease, cancer can cause manifestations in remote sites that are not directly affected by any focus of disease. Such manifestations of malignancy are collectivelly known as paraneoplastic phenomenon. Muscular manifestations consist of slight to severe and usually proximal wasting and weakness. In our laboratory we described the ultrastructural pathology of skeletal muscle in the paraneoplastic phenomenon in patients with bronchogenic and cervix carcinoma. In these studies a brief report on capillary alterations was made. The present investigation was undertaken in order to extent the study on the microvasculature in the skeletal muscle paraneoplastic phenomenon.Muscle biopsies were obtained in patients suffering from bronchogenic carcinoma (n= 10), gastric carcinoma (n= 7), cervix carcinoma (n= 1) and lymphoma (n= 4). Tissue samples were processed by routine transmission electron microscope techniques and observed in a Hitachi H-500 EM. |
| Databáze: | OpenAIRE |
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