Ultrasound guided FNA of thyroid performed by cytopathologists enhances Bethesda diagnostic value
| Autor: | Marita Teng, David Y. Zhang, Zesong Zhang, Eric M. Genden, Fadi Salem, David Burstein, Maoxin Wu, Brett A. Miles, YoonSun Choi, Quisheng Si, Arnold H. Szporn |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Gynecology
medicine.medical_specialty Histology Suspicious for Malignancy medicine.diagnostic_test business.industry Thyroid Bethesda system 030209 endocrinology & metabolism General Medicine Malignancy medicine.disease Bethesda system for reporting thyroid cytopathology Pathology and Forensic Medicine Surgical pathology 03 medical and health sciences 0302 clinical medicine Fine-needle aspiration medicine.anatomical_structure 030220 oncology & carcinogenesis Biopsy medicine Nuclear medicine business |
| Zdroj: | Diagnostic Cytopathology. 44:787-791 |
| ISSN: | 8755-1039 |
| DOI: | 10.1002/dc.23544 |
| Popis: | Background Ultrasound (US) guided fine needle aspiration (FNA) biopsy of thyroid are examined and reported by cytopathologists based usually on The Bethesda System for Reporting Thyroid Cytopathology (BTC) regardless of the procedure's performers. This study is designed to determine whether there is any performer-dependent difference. Methods Six hundred and fifty-one thyroid US-FNAs in correlation with surgical follow-up (SFU) were studied. The statistical analysis was performed using the surgical pathology diagnosis as the gold standard. Results Among the 283 cases performed by cytopathologists, there were 8 (2.8%) nondiagnostic (BTC I), 197 (69.6%) benign (BTC II), 31 (11%) atypical (BTC III), 14 (5%) suspicious for follicular neoplasm (BTC IV), 12 (4.2%) suspicious for malignancy (BTC V), and 21 (7.4%) positive for malignancy (BTC VI), and there were 55 (19.4%) cases with SFU. The 368 cases performed by others showed 76 (21%) BTC I, 238 (65%) BTC II, 26 (7%) BTC III, 10 (3%) BTC IV, 9 (2.5%) BTC V 5, and 9 (2.5%) BTC VI, and there were 26 (7%) cases with SFU. The cytopathologist group achieved better sensitivity (91.3 vs.78%); slightly better specificity (83.3 vs. 82%); better positive predictive value (87.5 vs. 70%); similar negative predictive value (88.2 vs. 88%); and better overall accuracy (87.8 vs. 81%) compared with the non-cytopathologist group. Overall the difference for all statistical values is significant different (P = 0.041). Conclusion US-FNA performed by cytopathologists showed a lower unsatisfactory rate and significantly better overall statistical values. Cytopathologists may play an important role in thyroid patient care. Diagn. Cytopathol. 2016;44:787–791. © 2016 Wiley Periodicals, Inc. |
| Databáze: | OpenAIRE |
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