The Changes in the Laboratory Values During Administration of Commercially Available Ready-to-use Basal Solutions for Total Parenteral Nutrition

Autor: Yasuhiro Kimura, Katsushi Miyake, Teruaki Kitaura, Shigeaki Arai, Hiroshi Fukuchi, Kenji Kihira, Masahiko Sakai, Hiroaki Ikeda, Eiji Sato
Rok vydání: 2001
Předmět:
Zdroj: Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 27:33-40
ISSN: 1882-1499
1346-342X
DOI: 10.5649/jjphcs.27.33
Popis: Some differences are seen in the concentrations of glucose and electrolytes between commercially available ready-to-use basal solutions for total parenteral nutrition (R-TPN).In this study, we investigated the effects of the long-term administration of Unicaliq®, which contains relatively higher concentrations of chloride ions than other R-TPNs, on the clinical laboratory values. One hundred and nineteen patients, who received Unicaliq® for more than four weeks at Hiroshima University Hospital, participated in this study. The laboratory values of chloride ion (Cl-) and blood urea nitrogen (BUN) significantly increased after receiving Unicaliq® for 2 weeks, but all levels, except for BUN, returned to the pretreatment levels after 4 weeks of administration. However, these changes were slight and all were within the normal ranges.No changes were observed in other laboratory values during the 4-week administration period.These results suggest that the clinical laboratory values are not affected by the long-term administration of Unicaliq®, at least up until 4 weeks.
Databáze: OpenAIRE