An unexpected one-pot synthesis of multi-substituted quinolines via a cascade reaction of Michael/Staudinger/aza-Wittig/aromatization of ortho-azido-β-nitro-styrenes with various carbonyl compounds

Autor:	Zhi-Hua Yu, De-Qing Shi, Ai-Dong Zhang, Hu-Fei Zheng, Wei Yuan, Zi-Long Tang
Rok vydání:	2013
Předmět:	Cascade reaction Chemistry Yield (chemistry) Organic Chemistry Drug Discovery Wittig reaction One-pot synthesis Nitro Aromatization Substrate (chemistry) Biochemistry Medicinal chemistry
Zdroj:	Tetrahedron. 69:8137-8141
ISSN:	0040-4020
DOI:	10.1016/j.tet.2013.07.050
Popis:	Multi-substituted quinolines 3 were unexpectedly prepared from a cascade reaction of ortho-azido-β-nitro-styrenes with various carbonyl compounds. This method takes advantages of mild condition, simple work-up, high yield as well as wide substrate scope, which makes this method powerful for one-pot synthesis of multi-substituted quinolines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::503086ba692fc33acfa260dc47cd11bb https://doi.org/10.1016/j.tet.2013.07.050 Zobrazit plný text záznamu Full Text from ScienceDirect