Role of Circulating Tumor Cells in Determining Prognosis in Metastatic Breast Cancer
| Autor: | Sonia Dhaka, Rupal Tripathi, Dinesh Chandra Doval, Anurag Mehta, Udip Maheshwari, Venkata Pradeep Babu Koyyala, Jatinderpal Singh |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | South Asian Journal of Cancer. 12:062-067 |
| ISSN: | 2278-4306 2278-330X |
| DOI: | 10.1055/s-0042-1753477 |
| Popis: | Background Circulating tumor cells (CTCs) in the peripheral blood may play a major role in the metastatic spread of breast cancer. This study was conducted to assess the role of CTCs to determine the prognosis in terms of survival in metastatic breast cancer patients. Methods This prospective study of 36 patients was conducted at the Hospital from April 2016 to May 2018. Details of each patient related to the demographic profile, tumor type, treatment, and follow-up information were recorded. The number of CTCs in the peripheral blood was measured by Celsee PREP 400 sample processing system and Celsee Analyzer imaging station. Results There was a positive correlation between the number of site of metastasis with number of CTCs (p-value Conclusion Assessment of CTCs provides a more quantifiable response than radiographic evaluation and at a much earlier time point and is also a better predictor of survival. |
| Databáze: | OpenAIRE |
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