| Autor: |
Marco Podobnik, Ajeet P. Singh, Zhenqiang Fu, Christopher M. Dooley, Hans Georg Frohnhöfer, Magdalena Firlej, Hadeer Elhabashy, Simone Weyand, John R. Weir, Jianguo Lu, Christiane Nüsslein-Volhard, Uwe Irion |
| Rok vydání: |
2022 |
| Popis: |
Teleost fish of the genusDanioare excellent models to study the genetic and cellular bases of pigment pattern variation in vertebrates. The two sister speciesDanio rerioandDanio aesculapiishow divergent patterns of horizontal stripes and vertical bars that are partly caused by the evolution of the potassium channel genekcnj13. InD. rerio, kcnj13is required in melanophores for interactions with xanthophores and iridophores, which cause location-specific pigment cell shapes and thereby influence colour pattern and contrast. Here, we show that cis-regulatory rather than protein coding changes underliekcnj13evolution between the two species.D. aesculapiiexpress lowerkcnj13levels and exhibit low-contrast patterns similar toD. reriomutants. Our results suggest that homotypic and heterotypic interactions between the pigment cells and their shapes diverged between species by quantitative changes inkcnj13expression during pigment pattern diversification. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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